Investigator(s)
| Submitter |
Sonam Gyeltshen Royal Centre for Disease Control Sonam Gyeltshen 
|
| Principal Investigator |
Sonam Gyeltshen Royal Centre for Disease Control Sonam Gyeltshen
|
| Co-Investigator(s) |
Tshering Dorji Royal Centre for Disease Control Tshering Dorji
|
Title(s) and abstract
| Scientific title | Re-emergence of DENV-3 (Genotype III), cause of the explosive dengue outbreak in Bhutan, 2019 |
| Public title | Re-emergence of DENV-3 (Genotype III), cause of the explosive dengue outbreak in Bhutan, 2019 |
| Background | Dengue is a mosquito-borne viral disease commonly reported in the tropical and subtropical regions of the world. In Bhutan, the disease is endemic in southern regions that favors the transmission of dengue due to their conducive environmental, climatic, ecological and social factors. In 2019, Bhutan was hit by an explosive outbreak that affected almost every region of the country. This retrospective study was undertaken to identify dengue virus serotype and genotype responsible for this outbreak and determine the possible source of infection. |
| Objectives | To perform molecular characterization of DENV from acute serum specimens collected from 2019 outbreaks in order to elucidate the molecular epidemiology of the DENV in Bhutan and ultimately help in the development of dengue control strategies and appropriate interventions suitable to the affected districts in the country. |
| Study Methods | Retrospective study |
| Expected outcomes and use of results | genomic molecular characterization of dengue virus that caused 2019 outbreak will be identified. Furthermore, analyzed data will be disseminated to relevant stake holders for control and intervention measures. |
| Keywords | Dengue fever, serotype, Dengue virus |
Research Details
| Student research | No |
| Start Date | 01-Jul-2024 |
| End Date | 31-Jan-2025 |
| Key Implementing Institution | Royal Centre for Disease Control |
| Multi-country research | No |
| Nationwide research | Yes |
| Research Domain(s) | Communicable Disease Research |
| Research field(s) | Infectious Disease |
| Involves human subjects | No |
| Data Collection | Secondary data |
| Proposal reviewed by other Committee | No |