Proposal Summary


Investigator(s)

Submitter Sonam Yoezer
Dechencholing Hospital
under JDWNRH

Internship with KGUMSB
Sonam Yoezer Mail
Principal Investigator Sonam Yoezer
Dechencholing Hospital
under JDWNRH

Internship with KGUMSB
Sonam Yoezer Mail
Co-Investigator(s) Dawa Gyeltshen
Department of Medicine
Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan
Dawa Gyeltshen Mail
Co-Investigator(s) Bikram Chhetri
Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan
Bikram Chhetri Mail
Co-Investigator(s) Saran Tenzin Tamang
Division of Medicine, Northern Adelaide Local Health Network, Australia
Saran Tenzin Tamang Mail
Co-Investigator(s) Zimba Lethro
Khesar Gyalpo University of Medical Sciences, Thimphu, Bhutan
Zimba Lethro Mail
Co-Investigator(s) Samten Wangchuk
Noble’s Hospital, Isle of Mann
Samten Wangchuk Mail
Co-Investigator(s) Ugyen Chophel
Department of General medicine, Wangdue Hospital, Wangdue Phodrang, Bhutan.
Ugyen Chophel Mail


Title(s) and abstract

Scientific title Knowledge, Attitude and Practices of Nicotine Replacement Therapy for Tobacco Cessation among Prescribers in Bhutan: a cross-sectional study
Public title Knowledge, Attitude and Practices of Nicotine Replacement Therapy for Tobacco Cessation among Prescribers in Bhutan
 
Background There are 8 million deaths from tobacco use annually, despite the reducing trend of tobacco use in High income countries over the last few decades. There is still a significant burden of tobacco in the Low and Middle Income Countries (LMIC). Nicotine Replacement Therapies (NRTs) have been shown to significantly help in long term and permanent tobacco smoking cessation. Therefore, understanding the knowledge, attitude and practices (KAP) of NRT among prescribers responsible in prescribing NRT is very crucial
Objectives Among the medical prescribers, who are actively working across various healthcare facility in Bhutan from May to July 2026, to describe the: 1. Level of knowledge Nicotine Replacement Therapy for Tobacco Cessation in Bhutan 2. Attitudes towards the Nicotine Replacement Therapy for Tobacco Cessation in Bhutan 3. Practices related to the Nicotine Replacement Therapy for Tobacco Cessation in Bhutan 4. Factors associated with knowledge, attitude, and practices regarding Nicotine Replacement Therapy for Tobacco Cessation in Bhutan
Study Methods The research methodology employs a cross-sectional study design to assess the knowledge, attitudes, and practices (KAP) of 1,006 health prescribers in Bhutan regarding Nicotine Replacement Therapy. Utilizing a stratified random sampling method to ensure national representativeness across all health tiers, a sample size of 307 participants was calculated using OpenEpi, accounting for a 10% dropout rate. Data collection will occur over three months between May and July 2026 via an online-administered survey on the REDCap platform. The survey instrument, developed through extensive literature review and validated by five experts with a Content Validity Index of 95.2%, will be pilot-tested among nurses to ensure linguistic and cultural clarity. Ethical safeguards include mandatory electronic informed consent and the subsequent deletion of identifying information, such as Citizenship Identity Card numbers, from the final dataset to maintain participant anonymity. Quantitative data analysis will be performed using STATA version 18.0, with socio-demographic profiles described through frequencies, proportions, and means. Knowledge and attitude levels are strictly categorized, with "good" performance requiring a threshold of at least 80%. Inferential statistics will utilize Chi-Square tests to examine associations between categorical variables, while Pearson or Spearman correlations will relate continuous variables, such as years of practice, to knowledge scores. To identify significant predictors of "good" knowledge, a log-binomial regression model will be employed to calculate odds ratios. Factors demonstrating a p-value of less than 0.1 in unadjusted analysis will be integrated into a final adjusted model, where a p-value of less than 0.05 will be the definitive threshold for statistical significance.
Expected outcomes and use of results The results of this study will be disseminated to health care providers, policy decision makers and doctors in Bhutan. The results will also be presented at national and international conferences and submitted for publication in a peer reviewed journal. We hope this research can help us guide future trainings and workshops.
 
Keywords Nicotine Replacement Therapy (NRT), prescribers, tobacco use cessation, health care worker


Research Details

Student research No
Start Date 20-Mar-2026
End Date 21-Mar-2027
Key Implementing Institution Ministry of Health
Multi-country research No
Nationwide research Yes
Research Domain(s) Non-communicable diseases & Healthy Lifestyles
Research field(s) Other (Tobacco cessation)
Involves human subjects Yes
  Population-Based Survey
Data Collection Primary data
Proposal reviewed by other Committee No