Investigator(s)
| Submitter |
Thinley Yangzom JDWNRH Thinley Yangzom 
|
| Principal Investigator |
Thinley Yangzom JDWNRH Thinley Yangzom
|
Title(s) and abstract
| Scientific title | Incidences of Urinary Tract Infection among pregnant women visiting Jetsun Pema Mother and Child Hospital, Jigme Dorji Wangchuk National Referral Hospital, Bhutan: A cross -sectional study. |
| Public title | Incidences of Urinary Tract Infection among pregnant women visiting Jetsun Pema Mother and Child Hospital, Jigme Dorji Wangchuk National Referral Hospital, Bhutan: A cross-sectional study. |
| Background | Urinary tract infections (UTIs) are one of the leading causes of higher morbidity and mortality in the developing countries1,2. UTI’s are commonly caused bacterial infections worldwide and it is most common problem faced during pregnancy. Symptomatic as well as asymptomatic UTIs are common during pregnancy due to physiological changes that can make women more susceptible encompassing a spectrum of adverse outcomes such as pyelonephritis, preterm birth, low birth weight, and neonatal sepsis5.However, the information about UTIs in pregnant women in Bhutan is limited and has not been investigated comprehensively. The main objective of this study is to determine the incidence of UTI among the pregnant women visiting the Jetsun Pema Mother and Child Hospital for antenatal checkup using fully automated urine particle analyzer (Sysmex UF 5000). This study will also attempt to assess overall effectiveness and usefulness of Sysmex UF 5000 in rapid diagnosis of UTI in healthcare setting of Bhutan. |
| Objectives | Objectives: a. To determine the incidence of UTI among pregnant women visiting the Jetsun Pema Mother and Child Hospital, Jigme Dorji Wangchuck National Referral Hospital using Sysmex UF 5000, auto-analyzer. b. To assess utility of Sysmex UF 5000 auto-analyzer in rapid diagnosis of UTI in pregnant women in healthcare setting of Bhutan. c. Assess the UF-5000 sensitivity and specificity in comparison to existing conventional urinalysis test. |
| Study Methods | Prospective and observational study. This study plans to enroll all the urine samples from pregnant women at Jetsun Pema Mother and Child Hospital, JDWNRH. A total of 2000 samples shall be collected within the six months. Due to lack of evidence on prevalence data of maternal UTI in Bhutan, the sample size is calculated based on the estimated prevalence rate of UTI in general patients, sensitivity and specificity from previous study. If the sample target could not be met within the stipulated time, another 3 months will be allocated to ensure required samples are collected. |
| Expected outcomes and use of results | To determine the incidence of UTI among the pregnant women visiting the Jetsun Pema Mother and Child Hospital for antenatal checkup using fully automated urine particle analyzer (Sysmex UF 5000). This study will also attempt to assess overall effectiveness and usefulness of Sysmex UF 5000 in rapid diagnosis of UTI in Bhutan and find out the clinical implications of maternal UTI in terms of neonatal outcomes in future research. |
| Keywords | Antenatal UTI Incidence GJPMCH |
Research Details
| Student research | No |
| Start Date | 01-Mar-2025 |
| End Date | 01-Mar-2026 |
| Key Implementing Institution | Jigme Dorji Wangchuck National Referral Hospital |
| Multi-country research | No |
| Nationwide research | No |
| Bhutan | |
| Research Domain(s) | Maternal, Reproductive and Child Health |
| Research field(s) | Infectious Disease |
| Involves human subjects | Yes |
| Other (Prospective observational) | |
| Data Collection | Primary data |
| Proposal reviewed by other Committee | No |